Realizing the full potential of DSF
Despite being a widely used technique for determining the apparent melting temperature of a purified protein, DSF has largely been treated as a secondary use case in the development of most high throughput thermal profiling technologies. At Mithlond Labs, we're building a first-class DSF High Throughput Screening Platform to realize the full potential of this well regarded in vitro technique.
Increased versatility
Our FS350 DSF Platform "Levels" support you wherever you are in your Protein Thermal Stability assay development journey: whether you have never generated a melt curve for your target, you've tried SPR but are looking to see if there's a more reagent efficient option, or you've tried Sypro and it gave weak or messy melt curves with no discernible Tm values.
Increased sensitivity
Precise fluorescence excitation and detection reduces background, while high dynamic range boosts intensity resolution
Decreased reagent input
design assays with <5 uL reactions and protein concentrations <1 uM
Increased Data Transparency
Access your raw fluorescent intensity readings on a transparent absolute scale, increasing insights into assay dynamics and readiness for Machine Learning
